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Beilstein J. Org. Chem. 2017, 13, 2252–2263, doi:10.3762/bjoc.13.222
Graphical Abstract
Figure 1: Molecular structures with atom numbering of the guest (a: from left to right): pemetrexed (PTX) and...
Figure 2: Dissociation efficiency curves of three CDs/PTX complexes. The ions were collided with nitrogen (pr...
Figure 3: The proposed molecular structures of PTX complexes with α-CD (a: exclusion-type), β-CD (b: rotaxane...
Figure 4: 2D ROESY NMR spectrum of an equimolar mixture of β-CD and PTX in D2O at 298 K. Inset: splitting of ...
Figure 5: 2D ROESY NMR spectra of a mixture of γ-CD with a 16-fold molar excess of PTX added in D2O at 298 K.
Figure 6: a) FTIR–ATR and b) Raman spectra of PTX together with its complexes with α-CD, β-CD and γ-CD.